Proteina-Complexa
Generate protein binders around a posed ligand.
Results
Loading starting example…
Method & evidence
Jointly generate protein sequence and all-atom coordinates around a checksum-bound ligand pose with the pinned Proteina-Complexa ligand checkpoint.
Scope & limitations
- The released operation is the single-pass ligand-binder workflow, not the separate protein-binder or motif-scaffolding checkpoints.
- Each output remains linked to the exact input pose, checkpoint, seed, and container image.
Interpreting results
- Generated geometry is a model proposal, not evidence of binding affinity or biochemical function.
- Ligand-conservation evidence proves coordinate identity within the output contract; it does not prove energetic favorability.
- Rank candidates with orthogonal structural evidence before experimental testing.
References
Input requirements & outputs
Input checks
- Exactly one checksum-verified PDB input
- At least one ligand heavy atom with the requested component identity
- 1–4 designs of 40–120 protein residues per Run
Expected results
- Generated sequence–structure cohort — Compare every designed protein sequence and its all-atom protein–ligand complex.
- Interactive complex structures — Open checksum-bound PDB artifacts in the 3D structure viewer.
- Ligand-conservation evidence — Verify requested component identity and ligand heavy atoms for each candidate.
