ImmuneBuilder
Predict antibody and VHH structures.
Results
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Method & evidence
Predict antibody or VHH coordinates and review residue-level uncertainty across the structural ensemble.
Scope & limitations
- This method supports antibody VH/VL and VHH structures, not TCR prediction.
Interpreting results
- Lower predicted coordinate error indicates greater model agreement, not experimental validation.
- Review CDR loops and unusual regions alongside ensemble uncertainty before structure-guided decisions.
- Confirm chain sequences and numbering before downstream modeling.
References
Input requirements & outputs
Input checks
- Heavy/VHH sequence for every selected row
- Paired light chain for VH/VL mode
- Up to 100 rows and 500 residues per sequence
Expected results
- Predicted structures — Open or download PDB coordinates for each successful prediction.
- Residue predicted error — Review ensemble coordinate-error evidence across each chain.
- Sequence conservation — Verify that published structures preserve the submitted chains.
