Generation method

Redesign a binder against a fixed protein target

Run FoldCraft against checksum-bound binder and target templates, then inspect every designed sequence, predicted complex, and stage-level score.

Method details

Input checks

  • Exactly one checksum-verified binder PDB and one target PDB
  • Explicit binder and target chains with valid target hotspot residue ranges
  • One to four trajectories in the released batch, with up to four ProteinMPNN samples each

Expected results

  • Designed sequences and ranked metrics — Compare trajectory, sequence, confidence, loss, and interface evidence in one table.
  • Predicted binder–target structures — Open each checksum-bound PDB in the shared 3D structure viewer.
  • Execution provenance — Retain templates, hotspots, models, parameters, image, request, result, and artifact digests.
Example results
Checking your workspace access…
Ubi Biologics