Analysis method
Map aggregation-prone regions on a structure
Score residues in a protein structure, locate contiguous positive-score regions, and review surface accessibility alongside aggregation propensity.
Method details
Input checks
- PDB structure with standard protein residues
- Optional single-chain selection
- Up to 4 structures and 8 MB total input per analysis
Expected results
- Residue propensity map — Scan aggregation scores in structure order with positive hotspots highlighted.
- Contiguous positive regions — Prioritize stretches of positive-scoring surface residues.
- Chain-level summary — Compare minimum, maximum, mean, and total scores across chains.
Example results
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